Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL1325894 | 0.94 | HDAC3 (0.41) | ALDH1A1KMOTDP2HPGDMEN1 | |
| Sebacic Acid SCHEMBL1326195 | 0.93 | HDAC3 (0.44) | ALDH1A1KMOTDP2LMNASMN1; SMN2 | |
| Isophthalic Acid SCHEMBL472832 | 0.92 | KMO (0.47) | ALDH1A1KMOHPGDMEN1GAA | |
| Isophthalic Acid SCHEMBL2133440 | 0.91 | KMO (0.46) | ALDH1A1KMOHPGDMEN1GAA | |
| Isophthalic Acid SCHEMBL1325825 | 0.90 | HDAC3 (0.42) | KMOTDP2PKMTSHRMEN1 | |
| Succinic Acid SCHEMBL1326223 | 0.89 | ALDH1A1 (0.45) | ALDH1A1PKMTSHRHPGDMEN1 | |
| Azelaic Acid SCHEMBL10396106 | 0.88 | HDAC3 (0.45) | ALDH1A1KMOTDP2PKMTSHR | |
| Isophthalic Acid SCHEMBL374460 | 0.87 | KMO (0.46) | ALDH1A1KMOHPGDMEN1GAA | |
| Isophthalic Acid SCHEMBL170729 | 0.87 | KMO (0.48) | ALDH1A1KMOTDP2HPGDMEN1 | |
| Terephthalic Acid SCHEMBL28482093 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1PKMTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024135597-A1 | METHOD FOR PRODUCING POLYESTER RESIN, AND POLYESTER RESIN | 東レ株式会社 | 2024-06-27 | — | — | WO | disclosed |
| CN-118234803-A | Thermoplastic polyester resin composition and molded article | 东丽株式会社 | 2024-06-21 | — | — | CN | disclosed |
| EP-3835340-B1 | MULTIAXIAL TEXTILE RESIN BASE MATERIAL AND METHOD FOR PRODUCTION THEREOF | TORAY INDUSTRIES (JP) | 2024-05-01 | — | — | EP | disclosed |
| EP-3970942-B1 | COMPOSITE MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-27 | — | — | EP | disclosed |
| EP-3608366-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-06 | — | — | EP | disclosed |
| WO-2024014339-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE CONTAINING SAME | ＵＢＥ株式会社 | 2024-01-18 | — | — | WO | disclosed |
| WO-2024004774-A1 | RECYCLED MONOMER, RECYCLED MONOMER PRODUCTION METHOD, AND RECYCLED MONOMER PRODUCTION DEVICE | 東レ株式会社 | 2024-01-04 | — | — | WO | disclosed |
| EP-3647367-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TORAY INDUSTRIES (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-115023467-B | Thermoplastic polyester resin composition and molded article | 东丽株式会社 | 2023-11-03 | — | — | CN | disclosed |
| CN-109757104-B | Thermoplastic resin composition and metal joint and method for producing same | 东丽先端材料研究开发（中国）有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-8574669-B2 | Method for producing polymer fine particle comprising contacting an emulsion with a poor solvent | TORAY INDUSTRIES, INC. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-8575246-B2 | Flame-retardant thermoplastic resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-2623542-A1 | POLYMER MICROPARTICLES AND PROCESS FOR PRODUCTION THEREOF | Toray Industries, Inc. (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20130183528-A1 | POLYMER MICROPARTICLES AND PROCESS FOR PRODUCTION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20120149837-A1 | THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2012-06-14 | — | — | US | disclosed |
| US-8193264-B2 | Thermoplastic resin composition and molded article thereof | TORAY INDUSTRIES, INC. (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20110275743-A1 | FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110070442-A1 | METHOD FOR PRODUCING POLYMER FINE PARTICLE | TORAY INDUSTRIES, INC. (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20090275678-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-2036952-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | Toray Industries, Inc. (JP) | 2009-03-18 | — | — | EP | disclosed |