Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL10396106 | 0.99 | HDAC3 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL1325894 | 0.96 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL1326195 | 0.94 | HDAC3 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL1324997 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2KMOTDP2PKMTSHR | |
| Terephthalic Acid SCHEMBL9267638 | 0.89 | HDAC3 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL170729 | 0.89 | KMO (0.48) | KMOTDP2CA12CA1CA2 | |
| Adipic Acid SCHEMBL9017423 | 0.88 | SMN1; SMN2 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL1325137 | 0.87 | HDAC3 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Terephthalic Acid SCHEMBL28482093 | 0.87 | SMN1; SMN2 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL374460 | 0.86 | KMO (0.46) | SMN1; SMN2KMOCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3970942-B1 | COMPOSITE MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-27 | — | — | EP | disclosed |
| CN-109757104-B | Thermoplastic resin composition and metal joint and method for producing same | 东丽先端材料研究开发（中国）有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230174837-A1 | THERMALLY CONDUCTIVE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME | TOYOBO CO., LTD. (JP) | 2023-06-08 | — | — | US | disclosed |
| US-11578185-B2 | Polyester resin composition, molded article, and composite molded article | TORAY INDUSTRIES, INC. (JP) | 2023-02-14 | — | — | US | disclosed |
| US-20220145044-A1 | POLYESTER RESIN COMPOSITION, MOLDED ARTICLE, AND COMPOSITE MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2022-05-12 | — | — | US | disclosed |
| US-11319436-B2 | Thermoplastic polyester resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2022-05-03 | — | — | US | disclosed |
| US-20200172726-A1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200171724-A1 | COMPOSITE MOLDED ARTICLE AND METHOD OF PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3031860-B1 | PREPREG BASED ON AN EPOXY RESIN COMPOSITION, AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-10239970-B2 | Method of producing fine particles of non-vinyl thermoplastic polymer | TORAY INDUSTRIES, INC. (JP) | 2019-03-26 | — | — | US | disclosed |
| US-8193264-B2 | Thermoplastic resin composition and molded article thereof | TORAY INDUSTRIES, INC. (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20110275743-A1 | FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110070442-A1 | METHOD FOR PRODUCING POLYMER FINE PARTICLE | TORAY INDUSTRIES, INC. (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20090275678-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-2036952-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | Toray Industries, Inc. (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-0536952-B1 | Method of draw-forming a metal sheet having an organic film | TOYO SEIKAN KAISHA LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0536952-A1 | Method of draw-forming a metal sheet having an organic film | TOYO SEIKAN KAISHA LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4535049-A | Pressure-fixing toner for electrophotography and process for preparation thereof | MITA INDUSTRIAL CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| US-4415645-A | PARTICLES OF A WAXY FIXATIVE DISPERSED IN A MOMOGENOUS MIXTURE OF RESIN AND PIGMENT; ANTIFOGGING AGENTS; TRANSFERRING | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1983-11-15 | — | — | US | disclosed |
| US-4357406-A | EMULSIFICATION, FIXING | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1982-11-02 | — | — | US | disclosed |