Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523648 | 0.85 | BCHE (0.47) | BCHECCKBR | |
| SCHEMBL10151339 | 0.84 | HTR2A (0.37) | BCHECCKBR | |
| SCHEMBL22582292 | 0.84 | BCHE (0.46) | CNR2BCHECCKBR | |
| SCHEMBL28756698 | 0.84 | BCHE (0.46) | CNR2BCHECCKBR | |
| SCHEMBL7074697 | 0.84 | BCHE (0.48) | BCHECCKBR | |
| SCHEMBL11371414 | 0.82 | BCHE (0.38) | SIGMAR1CNR2BCHEKDM4EALDH1A1 | |
| SCHEMBL13283171 | 0.82 | HTR6 (0.35) | SIGMAR1CCKBR | |
| SCHEMBL8261364 | 0.80 | HTR5A (0.41) | BCHEHPGDCCKBR | |
| SCHEMBL1488694 | 0.79 | HTR2A (0.46) | BCHEKDM4EMEN1KMT2AHSD17B10 | |
| Dimethylamine SCHEMBL8649623 | 0.79 | BCHE (0.39) | BCHEHPGDCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053462-B2 | Indole derivative and application thereof | SOMEI MASANORI | 2011-11-08 | — | — | US | disclosed |
| US-20070197629-A1 | Indole derivative and application thereof | SOMEI MASANORI | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197629-A1 | Indole derivative and application thereof | ARL1, IDO1, AIPL1 | SIGMAR1 1285/4885CNR2 1199/4885BCHE 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.