SCHEMBL1325645

SCHEMBL1325645

CC(C)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
TAAR1 Q96RJ0 6/20 0.33
LMNA P02545 3/20 0.33
SLC6A2 P23975 2/20 0.33
TSHR P16473 2/20 0.33
ALOX12 P18054 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
RIPK1 Q13546 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25909657 0.78 TAAR1 (0.41) TAAR1LMNATSHRADRA2AADRA2C
SCHEMBL25909658 0.78 TAAR1 (0.41) TAAR1LMNATSHRADRA2AADRA2C
SCHEMBL15302723 0.78 TAAR1 (0.33) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL12815293 0.78 TSHR (0.38) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL15302680 0.78 TDP1 (0.33) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL380702 0.77 TDP1 (0.36) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL18726525 0.76 THRB (0.38) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL8992273 0.74 TDP1 (0.35) TDP1TAAR1LMNASLC6A2TSHR
Fluoride SCHEMBL27639901 0.74 TDP1 (0.35) TDP1TAAR1LMNASLC6A2TSHR
SCHEMBL15915020 0.74 LMNA (0.38) TAAR1LMNASLC6A2TSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230258563-A1 DETECTION OF VOLATILES ISOBIONICS B V (NL) 2023-08-17 US claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
CN-117480220-A Antifouling paint composition and coating film 日本油漆船舶涂料公司 2024-01-30 CN disclosed
EP-4299684-A1 ANTIFOULING COATING COMPOSITION AND COATING FILM Nippon Paint Marine Coatings Co., Ltd. (JP) 2024-01-03 EP disclosed
EP-3693421-B1 ANTIFOULING PAINT COMPOSITION AND COATED ARTICLE HAVING ANTIFOULING COATING FORMED USING SAID COMPOSITION ON SURFACE NITTO KASEI CO LTD (JP) 2023-12-20 EP disclosed
US-20230258563-A1 DETECTION OF VOLATILES ISOBIONICS B V (NL) 2023-08-17 US disclosed
WO-2023277824-A2 DIVERSE FUNCTIONALIZATION OF HYDROSILANES AND PROGRAMMABLE SYNTHESIS OF MULTISUBSTITUTED ORGANOSILANES ENABLED BY NEUTRAL EOSIN Y PHOTOCATALYSIS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-01-05 WO disclosed
EP-4004538-A1 DETECTION OF VOLATILES Isobionics B.V. (NL) 2022-06-01 EP disclosed
CN-111886304-B Antifouling coating composition 日东化成株式会社 2022-02-01 CN disclosed
EP-3693426-B1 ANTIFOULING PAINT COMPOSITION AND COATED ARTICLE HAVING ANTIFOULING COATING FORMED USING SAID COMPOSITION ON SURFACE NITTO KASEI CO LTD (JP) 2021-12-29 EP disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed
WO-1996008503-A1 INTERMEDIATES FOR DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES NOVARTIS AG (CH) 1996-03-21 WO disclosed
WO-1996007666-A1 MONONUCLEOTIDE AND DINUCLEOTIDE ANALOGUES AND INTERMEDIATES THEREFOR NOVARTIS AG (CH) 1996-03-14 WO disclosed
WO-1995033761-A1 STEROID DERIVATIVES FOR TREATMENT OF 5 ALPHA REDUCTASE SMITHKLINE BEECHAM CORPORATION (US) 1995-12-14 WO disclosed
US-5466677-A Dinucleoside phosphinates and their pharmaceutical compositions CIBA-GEIGY CORPORATION (US) 1995-11-14 US disclosed
EP-0629633-A2 Dinucleotide analogues, intermediates therefor and oligonucleotides derived therefrom CIBA-GEIGY AG (CH) 1994-12-21 EP disclosed
EP-0614906-A1 Mononucleotide analogues and intermediates therefor CIBA-GEIGY AG (CH) 1994-09-14 EP disclosed
EP-0614907-A1 Dinucleotide and oligonucleotide analogues CIBA-GEIGY AG (CH) 1994-09-14 EP disclosed
EP-0567271-A2 Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses SANKYO COMPANY LIMITED (JP) 1993-10-27 EP disclosed