Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766700 | 0.90 | TRPV1 (0.54) | TRPV1MLYCDCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL766496 | 0.87 | TRPV1 (0.55) | TRPV1MLYCDCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL13256885 | 0.84 | MLYCD (0.52) | TRPV1MLYCD | |
| SCHEMBL1686298 | 0.76 | NOTUM (0.55) | CYP11B1CYP11B2ALDH1A1L3MBTL1KIF11 | |
| SCHEMBL766679 | 0.74 | TRPV1 (0.69) | TRPV1KIF11P2RX7 | |
| SCHEMBL1686549 | 0.74 | TRPV1 (0.59) | TRPV1CYP11B1CYP11B2KIF11P2RX7 | |
| SCHEMBL766613 | 0.73 | TRPV1 (0.56) | TRPV1CYP11B1CYP11B2KIF11P2RX7 | |
| SCHEMBL766813 | 0.73 | TRPV1 (0.62) | TRPV1MLYCD | |
| SCHEMBL1686447 | 0.73 | TRPV1 (0.61) | TRPV1CYP11B1CYP11B2KIF11P2RX7 | |
| SCHEMBL766505 | 0.73 | MLYCD (0.52) | TRPV1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091009-A1 | ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES | N.V. ORGANON (NL) | 2010-08-12 | — | — | WO | disclosed |