Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TACR1 | P25103 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.58 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18435552 | 0.87 | ALDH1A1 (0.84) | ALDH1A1GAAPOLBTSHRRAB9A | |
| SCHEMBL7293721 | 0.87 | ALDH1A1 (0.84) | ALDH1A1GAAPOLBTSHRRAB9A | |
| SCHEMBL1661081 | 0.81 | TRPV1 (0.76) | ALDH1A1GAAERCC1ERCC4L3MBTL1 | |
| SCHEMBL17335487 | 0.81 | KMT2A (0.70) | ALDH1A1ERCC1ERCC4 | |
| SCHEMBL9114227 | 0.80 | TACR1 (0.61) | TACR1GAAPOLBRAB9A | |
| SCHEMBL1565778 | 0.79 | MMP13 (0.69) | ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31329317 | 0.79 | ALDH1A1 (1.00) | ALDH1A1GAATSHRNPC1 | |
| SCHEMBL28732580 | 0.78 | ALDH1A1 (0.92) | ALDH1A1TSHRNPC1 | |
| SCHEMBL1535771 | 0.78 | MMP13 (0.67) | ALDH1A1TACR1ERCC1ERCC4RAB9A | |
| SCHEMBL9117035 | 0.78 | MTNR1A (0.65) | ALDH1A1TACR1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088450-A2 | METHODS FOR TREATING DISEASES ASSOCIATED WITH THE MODULATION OF SERCA | CELLADON CORPORATION (US) | 2010-08-05 | — | — | WO | disclosed |