Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021363 | 0.97 | HDAC1 (0.48) | CTSKALDH1A1GAAHDAC3HDAC1 | |
| SCHEMBL21020832 | 0.83 | CARM1 (0.51) | CTSKHDAC1HDAC6 | |
| SCHEMBL27478660 | 0.83 | CARM1 (0.51) | CTSKHDAC1HDAC6 | |
| SCHEMBL27478669 | 0.83 | CARM1 (0.51) | CTSKHDAC1HDAC6 | |
| SCHEMBL9816254 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GAAHDAC3HDAC1HDAC2 | |
| SCHEMBL21020862 | 0.81 | DRD2 (0.52) | CTSKCTSLCTSBSCN9A | |
| SCHEMBL13258119 | 0.80 | NPSR1 (0.61) | CTSKALDH1A1CTSLCTSB | |
| SCHEMBL7677937 | 0.79 | CTSK (0.45) | CTSKALDH1A1HDAC1HDAC6CTSL | |
| SCHEMBL7677943 | 0.79 | CTSK (0.45) | CTSKALDH1A1HDAC1HDAC6CTSL | |
| SCHEMBL5850357 | 0.79 | CHRM2 (0.45) | CTSKALDH1A1GAACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088450-A2 | METHODS FOR TREATING DISEASES ASSOCIATED WITH THE MODULATION OF SERCA | CELLADON CORPORATION (US) | 2010-08-05 | — | — | WO | disclosed |