Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677937 | 1.00 | CTSK (0.45) | CTSKCTSSCTSBHDAC1HDAC6 | |
| SCHEMBL1435950 | 0.90 | LMNA (0.40) | CTSBHDAC1HDAC6SCN9ANR1I3 | |
| SCHEMBL7677151 | 0.85 | HDAC1 (0.43) | CTSKCTSSCTSBHDAC1HDAC6 | |
| SCHEMBL7677157 | 0.85 | HDAC1 (0.43) | CTSKCTSSCTSBHDAC1HDAC6 | |
| SCHEMBL7673592 | 0.84 | HTR2A (0.56) | CTSKCTSSCTSBHDAC1HDAC6 | |
| SCHEMBL7674593 | 0.84 | HTR2A (0.56) | CTSKCTSBHDAC1HDAC6SCN9A | |
| SCHEMBL7674588 | 0.84 | HTR2A (0.56) | CTSKCTSBHDAC1HDAC6SCN9A | |
| SCHEMBL7673597 | 0.84 | HTR2A (0.56) | CTSKCTSSCTSBHDAC1HDAC6 | |
| SCHEMBL13258239 | 0.79 | CTSK (0.51) | CTSKCTSBHDAC1HDAC6SCN9A | |
| SCHEMBL7677907 | 0.79 | CTSS (0.42) | CTSKCTSSCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380238-B1 | FOR THERAPY OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM; DAMAGE TO THE CENTRAL NERVOUS SYSTEM; CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS; DIABETES INSIPIDUS, AND SLEEP APNEA | VERNALIS RESEARCH LIMITED (GB) | 2002-04-30 | — | — | US | disclosed |