Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TLR4 | O00206 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | IGSF11 | Q5DX21 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569630 | 0.86 | FADS1 (0.47) | LMNATP53TLR4RAB9APNP | |
| SCHEMBL13258395 | 0.83 | FADS1 (0.41) | LMNATP53PNPALDH1A1MEN1 | |
| SCHEMBL13258372 | 0.80 | ALDH1A1 (0.37) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL13258410 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL13257579 | 0.78 | PDE7A (0.38) | LMNAPNPALDH1A1KDM4EMEN1 | |
| SCHEMBL13257621 | 0.78 | APLNR (0.48) | LMNATP53 | |
| SCHEMBL13257622 | 0.77 | ALDH1A1 (0.41) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL13257499 | 0.77 | HSP90AA1 (0.35) | LMNATP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL13258368 | 0.76 | ALDH1A1 (0.40) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL13257587 | 0.76 | PDE7A (0.53) | LMNATP53ALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |