Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257621 | 0.91 | APLNR (0.48) | PDE7AESR1ESR2TSHRLMNA | |
| SCHEMBL13258410 | 0.87 | ALDH1A1 (0.39) | PDE7APDE7BTGM2ALDH1A1LMNA | |
| SCHEMBL13257458 | 0.85 | PDE7A (0.42) | PDE7APDE7BTGM2ALDH1A1LMNA | |
| SCHEMBL13258405 | 0.84 | PDE7A (0.38) | PDE7AALDH1A1GAATSHRLMNA | |
| SCHEMBL13257579 | 0.84 | PDE7A (0.38) | PDE7AALDH1A1GAALMNAMAPT | |
| SCHEMBL13258372 | 0.84 | ALDH1A1 (0.37) | PDE7APDE7BTGM2ALDH1A1LMNA | |
| SCHEMBL13257642 | 0.81 | PDE7A (0.51) | PDE7ANPSR1TGM2ALDH1A1GAA | |
| SCHEMBL13266433 | 0.81 | TSHR (0.45) | PDE7ANPSR1ALDH1A1GAATSHR | |
| SCHEMBL13258409 | 0.81 | LMNA (0.37) | PDE7APDE7BTGM2ALDH1A1GAA | |
| SCHEMBL2561473 | 0.80 | FADS1 (0.49) | PDE7ANPSR1ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |