Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13258391 | 0.81 | CTSS (0.41) | CTSSCTSKTRPA1MAOAMAOB | |
| SCHEMBL8347031 | 0.77 | LOXL2 (0.39) | TRPA1LMNAACENOS3NOS1 | |
| SCHEMBL9852734 | 0.77 | TRPA1 (0.42) | TRPA1CAPN1MAOAMAOBLMNA | |
| SCHEMBL25382819 | 0.73 | CAPN1 (0.47) | CAPN1ACECPA1 | |
| SCHEMBL3989376 | 0.73 | CAPN1 (0.47) | CAPN1ACECPA1 | |
| SCHEMBL2267800 | 0.72 | TDP1 (0.43) | TRPA1CAPN1NOS3NOS1NOS2 | |
| SCHEMBL2268714 | 0.72 | TDP1 (0.43) | TRPA1CAPN1NOS3NOS1NOS2 | |
| SCHEMBL25651870 | 0.71 | EPHX1 (0.41) | TRPA1LMNANOS3NOS1NOS2 | |
| SCHEMBL8693276 | 0.70 | TRPA1 (0.44) | TRPA1MAOAMAOBLMNACPA1 | |
| SCHEMBL2269305 | 0.67 | LOXL2 (0.43) | TRPA1DPP4DPP7MAOBCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |