SCHEMBL13258673

SCHEMBL13258673

O=C(CCNC(=O)OCC1c2ccccc2-c2ccccc21)OC1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.43
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
DUT P33316 4/20 0.40
SLC6A2 P23975 1/20 0.39
TDP1 Q9NUW8 2/20 0.36
DOT1L Q8TEK3 1/20 0.36
SLC28A1 O00337 1/20 0.35
SLC28A2 O43868 1/20 0.35
SLC29A1 Q99808 1/20 0.35
SLC28A3 Q9HAS3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyuridine SCHEMBL2231520 0.81 DUT (0.50) KMT2ADUT
SCHEMBL9664349 0.81 DUT (0.57) DUT
SCHEMBL3486981 0.77 SLC28A1 (0.47) KMT2ADOT1LSLC28A1SLC28A2SLC29A1
SCHEMBL19813627 0.77 RNASE1 (0.53) RNASE1POLBDUTSLC6A2SLC28A1
SCHEMBL12655473 0.75 KMT2A (0.44) RNASE1KMT2ASLC6A2
SCHEMBL20883495 0.75 RNASE1 (0.71) RNASE1KMT2APOLBDUTSLC6A2
SCHEMBL13901234 0.75 RNASE1 (0.52) RNASE1POLBDUTSLC6A2SLC28A1
SCHEMBL9693232 0.74 DUT (0.38) KMT2ADUTDOT1L
SCHEMBL13283117 0.74 RNASE1 (0.48) RNASE1SLC6A2
SCHEMBL11575205 0.74 SLC6A2 (0.54) RNASE1DUTSLC6A2SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190151-A1 FLUORESCENTLY LABELED NUCLEOSIDE TRIPHOSPHATES AND ANALOGS THEREOF FOR SEQUENCING NUCLEIC ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY 2010-07-29 US disclosed
US-20100190151-A1 FLUORESCENTLY LABELED NUCLEOSIDE TRIPHOSPHATES AND ANALOGS THEREOF FOR SEQUENCING NUCLEIC ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY 2010-07-29 US disclosed