SCHEMBL9664349

SCHEMBL9664349

O=C(NC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyuridine SCHEMBL2231520 0.88 DUT (0.50) DUT
SCHEMBL8725738 0.85
SCHEMBL9693232 0.81 DUT (0.38) DUT
SCHEMBL13258673 0.81 RNASE1 (0.43) DUT
SCHEMBL9663790 0.77 ST6GAL1 (0.36) DUT
SCHEMBL9663874 0.76 ADORA3 (0.44)
SCHEMBL9480169 0.76 PIN1 (0.39) DUT
SCHEMBL9811623 0.75 DUT (0.61) DUT
SCHEMBL9811618 0.75 DUT (0.61) DUT
SCHEMBL9662365 0.75 DUT (0.64) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US disclosed
US-5118802-A DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US disclosed
US-5015733-A Phosphoramidites and oligonucleotides derived therefrom CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1991-05-14 US disclosed
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US disclosed