Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782808 | 0.89 | RNASE1 (0.45) | — | |
| SCHEMBL9693591 | 0.88 | DUT (0.36) | DUTDOT1LMEN1KMT2ACYP3A4 | |
| SCHEMBL10489355 | 0.82 | RNASE1 (0.47) | — | |
| SCHEMBL9693301 | 0.81 | DOT1L (0.38) | DOT1L | |
| SCHEMBL9664349 | 0.81 | DUT (0.57) | DUT | |
| SCHEMBL9782841 | 0.80 | CYP3A4 (0.33) | DOT1LCYP3A4CYP2C9 | |
| SCHEMBL9782837 | 0.78 | RNASE1 (0.41) | — | |
| SCHEMBL9782858 | 0.75 | RNASE1 (0.42) | — | |
| SCHEMBL13258673 | 0.74 | RNASE1 (0.43) | DUTDOT1LKMT2A | |
| SCHEMBL9693305 | 0.74 | RNASE1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |