Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402642 | 0.82 | LMNA (0.51) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL13259552 | 0.77 | POLB (0.35) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL5432274 | 0.77 | POLB (0.57) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL14466825 | 0.76 | POLB (0.41) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL537595 | 0.73 | SMN1; SMN2 (0.38) | LMNAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL13184169 | 0.73 | LMNA (0.55) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL28724747 | 0.73 | LMNA (0.43) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL6744945 | 0.71 | LMNA (0.58) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL9518977 | 0.71 | LMNA (0.54) | LMNAKMT2AMAPTHTTNCOA1 | |
| SCHEMBL4625127 | 0.71 | LMNA (0.54) | LMNAKMT2AMAPTHTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084868-A2 | TREATMENT OF DISORDERS BY ACTIVATION OF THE UNFOLDED PROTEIN RESPONSE | KALYPSYS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |