Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411525 | 0.86 | HSP90AA1 (0.44) | PTGDRPTGDR2OPRL1S1PR4S1PR1 | |
| SCHEMBL27537246 | 0.84 | SLC6A9 (0.46) | PTGDRPTGDR2PTGS2SLC6A9POLB | |
| SCHEMBL10091179 | 0.83 | DGAT1 (0.37) | FFAR4HSD17B1HSD17B2 | |
| SCHEMBL11763790 | 0.81 | PTGS2 (0.49) | PTGDRPTGDR2PTGS2SLC6A9POLB | |
| SCHEMBL14271037 | 0.80 | HSD17B1 (0.34) | OPRL1FFAR4HSD17B1HSD17B2 | |
| SCHEMBL18568795 | 0.79 | S1PR1 (0.39) | PTGDRPTGDR2OPRL1FFAR4S1PR4 | |
| SCHEMBL18458712 | 0.79 | ESR2 (0.42) | PTGDRPTGDR2PTGS2OPRL1FFAR4 | |
| SCHEMBL18854996 | 0.79 | S1PR1 (0.39) | PTGDRPTGDR2OPRL1FFAR4S1PR4 | |
| SCHEMBL18458513 | 0.78 | CYP3A4 (0.57) | FFAR4S1PR1S1PR5 | |
| SCHEMBL18411545 | 0.78 | CYP3A4 (0.57) | FFAR4S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171439-A1 | Inhibitors Of Histone Deacetylase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-06-19 | — | — | US | disclosed |
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171439-A1 | Inhibitors Of Histone Deacetylase | HDAC1, HDAC3, HDAC11 | PTGDR 3978/4885PTGDR2 4212/4885PTGS2 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.