SCHEMBL13263287

SCHEMBL13263287

C=CC1CCC(C2CCC(c3ccc(-c4ccc(-c5cccc(F)c5F)cc4)cc3F)CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.32
F10 P00742 1/20 0.32
WDR5 P61964 1/20 0.31
WNT1 P04628 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960966 0.85 DGAT1 (0.32)
SCHEMBL9019178 0.84
SCHEMBL13000540 0.83
SCHEMBL8961252 0.82 TDP2 (0.34)
SCHEMBL8961118 0.82 DGAT1 (0.32)
SCHEMBL14271037 0.82 HSD17B1 (0.34) FFAR4
SCHEMBL13000535 0.82
SCHEMBL8934263 0.81 DGAT1 (0.33)
SCHEMBL8961116 0.81 HTR2C (0.33) FFAR4
SCHEMBL8961305 0.81 NAAA (0.33) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206695-B1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2013-09-18 EP disclosed
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed