SCHEMBL13264635

SCHEMBL13264635

Bc1ccc(CI)c(O)c1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.38
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17928534 0.76 TYR (0.65) TYRALOX5
SCHEMBL12376872 0.74 TYR (0.39) TYRALOX5
SCHEMBL28646542 0.73 CASP1 (0.46) TYR
SCHEMBL14430064 0.73 TRPA1 (0.52) TYR
SCHEMBL14620990 0.71 ALDH1A1 (0.34) ALOX5
SCHEMBL12667819 0.69
SCHEMBL17928543 0.69 MEN1 (0.40) TYR
SCHEMBL16302570 0.69
SCHEMBL14620991 0.68
SCHEMBL7528271 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904047-B1 APOPTOSIS PROMOTERS ABBOTT LAB (US) 2013-01-02 EP disclosed
US-7750004-B2 Apoptosis promoters ABBOTT LABORATORIES (US) 2010-07-06 US disclosed