Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703043 | 0.83 | ADRA2A (0.49) | KMT2AMAPK1MEN1 | |
| SCHEMBL13263785 | 0.80 | MEN1 (0.47) | ALDH1A1KMT2APARP10TP53MEN1 | |
| SCHEMBL6742113 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10POLBGLA | |
| SCHEMBL6745168 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10POLBGLA | |
| SCHEMBL13265124 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KMT2APARP10POLBGLA | |
| SCHEMBL12203680 | 0.72 | LMNA (0.42) | ALDH1A1LMNATP53HPGDHSD17B10 | |
| SCHEMBL10187311 | 0.72 | CA12 (0.42) | ALDH1A1KMT2APARP10POLBBRD4 | |
| SCHEMBL24013661 | 0.71 | MEN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL12202047 | 0.71 | MEN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL12889913 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10POLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |