Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265121 | 0.83 | ALDH1A1 (0.44) | MEN1MAPK1KMT2A | |
| SCHEMBL19667851 | 0.82 | ADRA2A (0.53) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL13263785 | 0.81 | MEN1 (0.47) | MEN1KMT2AHTTAKR1C3AKR1C2 | |
| SCHEMBL14570523 | 0.78 | GAA (0.50) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL9027230 | 0.78 | ADRA1A (0.69) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL14691495 | 0.77 | ADRA2A (0.49) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL6796164 | 0.77 | ADRA2A (0.49) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL31119047 | 0.77 | ADRA2A (0.49) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL12248178 | 0.74 | ADRA2A (0.46) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL11709428 | 0.74 | ADRA2A (0.54) | ADRA2AADRA1ACYP2D6MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022740-A2 | GPR35 LIGANDS AND THE USES THEREOF | CORNING INCORPORATED (US) | 2013-02-14 | — | — | WO | disclosed |