Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265925 | 0.88 | KCNMA1 (0.56) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL7374064 | 0.83 | MEN1 (0.78) | MEN1KMT2ARORCMAPTALDH1A1 | |
| SCHEMBL14537856 | 0.82 | MAPT (0.71) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL13265680 | 0.82 | SETD7 (0.60) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL13265671 | 0.81 | MEN1 (0.65) | MEN1KMT2ARORCMAPTALDH1A1 | |
| SCHEMBL13265674 | 0.80 | THRA (0.55) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL13240465 | 0.79 | LOXL2 (0.55) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL8710534 | 0.79 | SIRT2 (0.60) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL13265678 | 0.76 | THRA (0.53) | MEN1KMT2AMAPTTHRAALDH1A1 | |
| SCHEMBL3528493 | 0.76 | EPHX1 (0.78) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |