Sugi Predict

Sugi Predict / Compounds / SCHEMBL132660

SCHEMBL132660

SCHEMBL132660

COc1ccc(CO[C@H]2[C@H]3OC(C)(C)O[C@H]3OC2(CO)CO)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GLA P06280 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ SLC5A1 P13866 1/20 0.36
▸ SLC5A2 P31639 1/20 0.36
▸ IDO1 P14902 2/20 0.36
▸ AGXT P21549 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ CALM1 P0DP23 1/20 0.33
▸ NAAA Q02083 1/20 0.33
▸ APP P05067 3/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511260 1.00 MEN1 (0.41) MEN1KMT2AGLANPSR1SLC5A1
SCHEMBL132697 0.92 MEN1 (0.39) MEN1KMT2AGLANPSR1SLC5A1
SCHEMBL18568726 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL1096325 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL10158814 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL24371821 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL7865382 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL14929223 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL6839631 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1
SCHEMBL2308101 0.86 ALDH1A1 (0.38) MEN1KMT2AIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9464106-B2 Oligonucleotides useful for detecting and analyzing nucleic acids of interest EXIQON A/S (DK) 2016-10-11 — — US disclosed
US-20120157333-A1 OLIGONUCLEOTIDES USEFUL FOR DETECTING AND ANALYZING NUCLEIC ACIDS OF INTEREST EXIQON A/S (DK) 2012-06-21 — — US disclosed
EP-1446412-B1 NOVEL LNA COMPOSITIONS AND USES THEREOF EXIQON AS (DK) 2012-03-07 — — EP disclosed
US-20070117144-A1 Oligonucleotides useful for detecting and analyzing nucleic acids of interest EXIQON A/S (DK) 2007-05-24 — — US disclosed
US-20040219565-A1 Oligonucleotides useful for detecting and analyzing nucleic acids of interest EXIQON A/S (DK) 2004-11-04 — — US disclosed
US-20030224377-A1 Novel LNA compositions and uses thereof QIAGEN GMBH (DE) 2003-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040219565-A1 Oligonucleotides useful for detecting and analyzing nucleic acids of interest UPF1, DCLRE1B, SNRPA1 MEN1 2069/4885KMT2A 2665/4885GLA 2435/4885
US-20030224377-A1 Novel LNA compositions and uses thereof RNGTT, NCL, NSUN2 MEN1 1124/4885KMT2A 1689/4885GLA 2248/4885
US-20120157333-A1 OLIGONUCLEOTIDES USEFUL FOR DETECTING AND ANALYZING NUCLEIC ACIDS OF INTEREST UPF1, DCLRE1B, SNRPA1 MEN1 2069/4885KMT2A 2665/4885GLA 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.