Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266500 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13266640 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13266731 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13452319 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13242965 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13266537 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13266534 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL14047645 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13242969 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13266786 | 0.80 | ALDH1A1 (0.43) | SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759291-B2 | Pyrazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20090192208-A1 | Pyrazole compounds and use thereof in noxious arthropod pests controlling composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192208-A1 | Pyrazole compounds and use thereof in noxious arthropod pests controlling composition | TRPA1, ACHE, MORF4L1 | SMN1; SMN2 3215/4885CYP1A2 414/4885CYP2C9 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.