Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 2/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244709 | 0.90 | HRH3 (0.58) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL1014002 | 0.79 | HPGD (0.86) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL1450838 | 0.77 | HRH3 (0.78) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL13267473 | 0.77 | HRH3 (0.60) | HRH3HPGDSMN1; SMN2AKR1C3 | |
| SCHEMBL13636330 | 0.76 | HRH3 (1.00) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL3456205 | 0.76 | HPGD (1.00) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL254490 | 0.76 | HRH3 (0.72) | HRH3HPGD | |
| SCHEMBL10184001 | 0.75 | HRH3 (0.78) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| Hydrochloric Acid SCHEMBL1177194 | 0.75 | HRH3 (0.97) | HRH3HPGDSMN1; SMN2USP2TSHR | |
| SCHEMBL18023314 | 0.74 | HRH3 (0.64) | HRH3HPGDSMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2008154642-A2 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | HRH3 4192/4885HPGD 307/4885SMN1; SMN2 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.