Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168575 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL22227819 | 0.86 | SLC6A2 (0.56) | HPGDSMN1; SMN2NPC1RAB9AOPRD1 | |
| SCHEMBL20832766 | 0.86 | SLC6A2 (0.56) | HPGDSMN1; SMN2NPC1RAB9AOPRD1 | |
| SCHEMBL14256052 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL26199245 | 0.84 | MC4R (0.54) | ALDH1A1HPGDLMNAOPRD1KDM4E | |
| SCHEMBL1013432 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1OPRD1CYP3A4 | |
| SCHEMBL13267282 | 0.83 | TSHR (0.54) | ALDH1A1HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL14709795 | 0.82 | KDM4E (0.46) | ALDH1A1HPGDALOX15MGLLHSD17B10 | |
| SCHEMBL1978575 | 0.82 | OPRD1 (0.69) | SMN1; SMN2NPC1RAB9AOPRD1MAPT | |
| SCHEMBL26199219 | 0.82 | OPRD1 (0.69) | SMN1; SMN2NPC1RAB9AOPRD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271933-A1 | HETEROCYCLIC IMMUNOMODULATOR | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271933-A1 | HETEROCYCLIC IMMUNOMODULATOR | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271933-A1 | HETEROCYCLIC IMMUNOMODULATOR | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| EP-4177247-A1 | HETEROCYCLIC IMMUNOMODULATOR | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2023-05-10 | — | — | EP | disclosed |
| EP-4177247-A1 | HETEROCYCLIC IMMUNOMODULATOR | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2023-05-10 | — | — | EP | disclosed |
| CN-115776983-A | Heterocyclic immunomodulators | 北京诺诚健华医药科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| WO-2022007659-A1 | HETEROCYCLIC IMMUNOMODULATOR | 北京诺诚健华医药科技有限公司 | 2022-01-13 | — | — | WO | disclosed |
| CN-113896711-A | Heterocyclic immunomodulators | 北京诺诚健华医药科技有限公司 | 2022-01-07 | — | — | CN | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271933-A1 | HETEROCYCLIC IMMUNOMODULATOR | IL2, ICOS, IL5 | ALDH1A1 233/4885HPGD 31/4885ALOX15 203/4885 |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | ALDH1A1 687/4885HPGD 307/4885ALOX15 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.