Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 9/20 | 0.79 |
| ▸ | F2 | P00734 | 8/20 | 0.79 |
| ▸ | PLAU | P00749 | 1/20 | 0.79 |
| ▸ | F10 | P00742 | 3/20 | 0.63 |
| ▸ | FURIN | P09958 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3128603 | 0.89 | NQO2 (0.66) | ST14F2PLAUF10FURIN | |
| SCHEMBL17084494 | 0.89 | ST14 (1.00) | ST14F2PLAUF10FURIN | |
| SCHEMBL483100 | 0.89 | ST14 (1.00) | ST14F2PLAUF10FURIN | |
| SCHEMBL523255 | 0.87 | LMNA (0.59) | ST14F2PLAUF10PRSS1 | |
| Iodide SCHEMBL3773658 | 0.84 | LMNA (0.56) | ST14F2PLAUF10PRSS1 | |
| Hydrochloric Acid SCHEMBL1019443 | 0.84 | PRSS1 (0.61) | ST14F2PLAUF10PRSS1 | |
| Hydrochloric Acid SCHEMBL22686316 | 0.82 | PRSS1 (0.58) | ST14F2PLAUF10PRSS1 | |
| Hydrochloric Acid SCHEMBL9342671 | 0.82 | LMNA (0.54) | ST14F2PLAUF10PRSS1 | |
| SCHEMBL19286912 | 0.81 | ST14 (0.83) | ST14F2PLAUF10FURIN | |
| SCHEMBL3085721 | 0.81 | F2 (0.83) | ST14F2PLAUF10FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265866-B1 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-07-21 | — | — | EP | disclosed |