Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.83 |
| ▸ | F2 | P00734 | 7/20 | 0.83 |
| ▸ | PLAU | P00749 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | F10 | P00742 | 3/20 | 0.66 |
| ▸ | FURIN | P09958 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084494 | 0.91 | ST14 (1.00) | ST14F2PLAUF10FURIN | |
| SCHEMBL483100 | 0.91 | ST14 (1.00) | ST14F2PLAUF10FURIN | |
| SCHEMBL563315 | 0.86 | LMNA (1.00) | ST14F2PLAULMNAF10 | |
| Hydrochloric Acid SCHEMBL4279969 | 0.84 | LMNA (0.94) | ST14F2PLAULMNAF10 | |
| Water SCHEMBL10917300 | 0.84 | LMNA (0.94) | ST14F2PLAULMNAF10 | |
| SCHEMBL3085721 | 0.83 | F2 (0.83) | ST14F2PLAUF10FURIN | |
| SCHEMBL20364177 | 0.81 | ST14 (0.79) | ST14F2PLAUF10FURIN | |
| SCHEMBL13270794 | 0.81 | ST14 (0.79) | ST14F2PLAUF10FURIN | |
| SCHEMBL6579180 | 0.79 | F2 (1.00) | ST14F2PLAUF10FURIN | |
| SCHEMBL26416903 | 0.78 | PARP10 (1.00) | ST14F2PARP10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745287-B2 | Pyrimidines and use thereof | PURDUE PHARMA L.P. (US) | 2017-08-29 | — | — | US | disclosed |