SCHEMBL523255

SCHEMBL523255

N=C(N)c1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
PLAU P00749 2/20 0.59
MASP2 O00187 1/20 0.59
THPO P40225 1/20 0.59
PRSS1 P07477 6/20 0.56
PRSS3 P35030 4/20 0.56
F2 P00734 3/20 0.56
APEX1 P27695 1/20 0.56
F10 P00742 2/20 0.55
NQO2 P16083 1/20 0.55
F12 P00748 1/20 0.55
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PKM P14618 1/20 0.55
ST14 Q9Y5Y6 1/20 0.54
PRMT5 O14744 1/20 0.54
PRMT1 Q99873 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1019443 0.97 PRSS1 (0.61) LMNAPLAUMASP2THPOPRSS1
Iodide SCHEMBL3773658 0.97 LMNA (0.56) LMNAPLAUMASP2THPOPRSS1
Hydrochloric Acid SCHEMBL9342671 0.95 LMNA (0.54) LMNAPLAUMASP2THPOPRSS1
Hydrochloric Acid SCHEMBL22686316 0.95 PRSS1 (0.58) LMNAPLAUMASP2THPOPRSS1
Alcohol SCHEMBL27821190 0.89 PRSS1 (0.54) LMNAPLAUMASP2THPOPRSS1
Acetic Acid SCHEMBL6179057 0.87 NQO2 (0.73) PRSS1PRSS3F2F10NQO2
SCHEMBL8722515 0.87 PRSS1 (0.55) LMNAPLAUMASP2THPOPRSS1
SCHEMBL13270794 0.87 ST14 (0.79) PLAUPRSS1PRSS3F2F10
SCHEMBL537030 0.85 LMNA (0.77) LMNAPLAUMASP2THPOPRSS1
Hydrochloric Acid SCHEMBL392375 0.82 PRSS1 (0.78) LMNAPLAUMASP2THPOPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113383039-B Moisture curable polyolefin formulation 陶氏环球技术有限责任公司 2023-09-26 CN claimed
US-20220098432-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-03-31 US claimed
EP-3924419-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION Dow Global Technologies LLC (US) 2021-12-22 EP claimed
CN-113383039-A Moisture curable polyolefin formulations 陶氏环球技术有限责任公司 2021-09-10 CN claimed
WO-2020164004-A1 MOISTURE-CURABLE POLYOLEFIN FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-08-20 WO claimed
CN-121038504-B Perovskite composite layer, preparation method thereof, perovskite device and photovoltaic module Chengdu Jingxin Mingneng Photovoltaic Technology Co.,Ltd. (CN) 2026-05-26 CN disclosed
WO-2025072330-A1 KIT INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2025-04-03 WO disclosed
US-20240262832-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF VANQUA BIO, INC. (US) 2024-08-08 US disclosed
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD SPRINGWORKS THERAPEUTICS, INC. (US) 2024-07-09 US disclosed
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD SPRINGWORKS THERAPEUTICS, INC. (US) 2024-07-09 US disclosed
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
EP-4329881-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF Vanqua Bio, Inc. (US) 2024-03-06 EP disclosed
EP-0497852-B1 BICYCLO-IMIDAZOLES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM BOEHRINGER MANNHEIM GMBH (DE) 1995-12-20 EP disclosed
WO-1995019358-A1 HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES SANDOZ LTD. (CH) 1995-07-20 WO disclosed
WO-1995010519-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1995-04-20 WO disclosed
EP-0527889-A4 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LAB (US) 1994-08-10 EP disclosed
EP-0527889-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1993-02-24 EP disclosed
EP-0497852-A1 BICYCLO-IMIDAZOLES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM. BOEHRINGER MANNHEIM GMBH (DE) 1992-08-12 EP disclosed
WO-1991016894-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1991-11-14 WO disclosed
WO-1991006545-A1 BICYCLO-IMIDAZOLES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM BOEHRINGER MANNHEIM GMBH (DE) 1991-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262832-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF GBA1, GAA, GBA2 LMNA 2954/4885PLAU 1834/4885MASP2 1071/4885
US-12030866-B2 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD YAP1, TEAD3, TEAD2 LMNA 2104/4885PLAU 3588/4885MASP2 3750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.