SCHEMBL3085721

SCHEMBL3085721

N=C(N)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F2 P00734 8/20 0.83
ST14 Q9Y5Y6 8/20 0.83
PLAU P00749 1/20 0.83
F10 P00742 4/20 0.78
FURIN P09958 1/20 0.78
PRSS1 P07477 6/20 0.67
PRSS2 P07478 6/20 0.67
PRSS3 P35030 6/20 0.67
PARP10 Q53GL7 1/20 0.64
F12 P00748 1/20 0.62
F7 P08709 1/20 0.62
F3 P13726 1/20 0.62
PKM P14618 1/20 0.62
BLM P54132 1/20 0.60
WDR5 P61964 1/20 0.59
C1S P09871 1/20 0.58
RECQL P46063 1/20 0.58
KMT2A Q03164 1/20 0.58
TMPRSS6 Q8IU80 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17084494 0.91 ST14 (1.00) F2ST14PLAUF10FURIN
SCHEMBL483100 0.91 ST14 (1.00) F2ST14PLAUF10FURIN
SCHEMBL6579180 0.88 F2 (1.00) F2ST14PLAUF10FURIN
SCHEMBL14519335 0.85 F2 (0.72) F2ST14PLAUF10FURIN
Diphenylether SCHEMBL28792708 0.84 LTA4H (0.67) F2ST14PLAUF10FURIN
SCHEMBL30583351 0.83 PLAU (0.63) F2ST14PLAUF10FURIN
SCHEMBL19286912 0.83 ST14 (0.83) F2ST14PLAUF10FURIN
SCHEMBL15339481 0.82 PRSS1 (0.66) F2ST14PLAUF10PRSS1
SCHEMBL20364177 0.81 ST14 (0.79) F2ST14PLAUF10FURIN
SCHEMBL13270794 0.81 ST14 (0.79) F2ST14PLAUF10FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107848959-B Halogen-substituted phenoxyphenylamidines and their use as fungicides 先正达农作物保护股份公司 2021-07-27 CN claimed
US-10912297-B2 Phenoxyhalogenphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-02-09 US claimed
EP-3307707-B1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2020-10-07 EP claimed
US-20200068886-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2020-03-05 US claimed
EP-3307706-B1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2019-07-24 EP claimed
US-10252977-B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-09 US claimed
US-20180199571-A1 PHENOXYHALOGENPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-19 US claimed
US-20180186724-A1 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-05 US claimed
US-20180153167-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2018-06-07 US claimed
EP-3319937-A1 PHENOXYHALOGENPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-05-16 EP claimed
EP-2120560-A1 4-CYCLOALKYL OR 4-ARYL SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2009-11-25 EP claimed
EP-2120558-A2 3,4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES Bayer CropScience AG (DE) 2009-11-25 EP claimed
WO-2008110315-A1 4-CYCLOALKYL OR 4-ARYL SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE TEHROF AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2008-09-18 WO claimed
WO-2008110280-A2 PHENOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO claimed
WO-2008110313-A1 PHENOXYPHENYLAMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO claimed
WO-2008110281-A2 3,4-DISUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO claimed
EP-1969930-A1 Phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed
EP-1969935-A1 3.4-disubstituted phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed
EP-1969934-A1 4-cycloalkyl or 4-aryl substituted phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed
EP-1969932-A1 Phenoxy substituted phenylamidine derivatives and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180199571-A1 PHENOXYHALOGENPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES DDT, PAH, CYP1A2 F2 1912/4885ST14 2452/4885PLAU 3280/4885
US-10912297-B2 Phenoxyhalogenphenylamidines and the use thereof as fungicides DDT, PAH, CYP1A2 F2 1912/4885ST14 2452/4885PLAU 3280/4885
US-20180153167-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES PFAS, DDT, PAH F2 2547/4885ST14 3308/4885PLAU 3878/4885
US-20200068886-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES PFAS, DDT, PAH F2 2547/4885ST14 3308/4885PLAU 3878/4885
US-10252977-B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides PFAS, DDT, PAH F2 2547/4885ST14 3308/4885PLAU 3878/4885
US-20180186724-A1 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides PFAS, DDT, PAH F2 2547/4885ST14 3308/4885PLAU 3878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.