Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 2/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271481 | 0.84 | L3MBTL1 (0.39) | GAAMAPTNAMPT | |
| SCHEMBL10233313 | 0.81 | GAA (0.49) | CHRNB2CHRNA4GAAMAPT | |
| SCHEMBL14144201 | 0.81 | KCNQ3 (0.39) | NAMPT | |
| SCHEMBL13271647 | 0.77 | CHRNB2 (0.35) | CHRNB2CHRNA4GAAMAPT | |
| SCHEMBL3535333 | 0.73 | GAA (0.62) | ITGB1ITGA5GAAMAPT | |
| SCHEMBL14143435 | 0.73 | GPR132 (0.39) | ITGB1 | |
| SCHEMBL2608565 | 0.72 | GAA (0.51) | ITGB1GAAMAPT | |
| SCHEMBL13891413 | 0.70 | PYGL (0.52) | PYGLGAAMAPT | |
| SCHEMBL29301436 | 0.67 | MAPT (0.49) | GAAMAPT | |
| SCHEMBL14548031 | 0.66 | CHRNB2 (0.40) | CHRNB2CHRNA4GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LTD (GB) | 2010-07-14 | — | — | EP | disclosed |