Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733501 | 0.86 | KIF11 (0.51) | KMOCTSSKDM4EALDH1A1LMNA | |
| SCHEMBL2788482 | 0.81 | CCNT1 (0.63) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL11469890 | 0.81 | KMO (0.62) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL16629561 | 0.81 | KMO (0.58) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL21116043 | 0.81 | CSNK1A1 (0.58) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL11467792 | 0.81 | LMNA (0.58) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL2609384 | 0.81 | KMO (0.58) | KMOCTSSKDM1AKDM4EALDH1A1 | |
| SCHEMBL31301320 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1IDO1LMNACDK2 | |
| SCHEMBL15888381 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1IDO1LMNACDK2 | |
| SCHEMBL13692259 | 0.79 | ABL1 (0.58) | KMOCTSSKDM1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785445-B2 | 7-phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2014-07-22 | — | — | US | disclosed |
| WO-2010075200-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2010-07-01 | — | — | WO | disclosed |