Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 6/20 | 0.32 |
| ▸ | ACACA | Q13085 | 6/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128961 | 0.86 | JAK2 (0.35) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL13273300 | 0.85 | ACACB (0.42) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL13273769 | 0.76 | TDP2 (0.34) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL13284272 | 0.76 | HDAC1 (0.33) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL11940679 | 0.74 | HSD17B1 (0.39) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL12118986 | 0.74 | HSD17B1 (0.43) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL12129034 | 0.73 | ACACB (0.36) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL12128964 | 0.73 | ACACB (0.46) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL12119027 | 0.72 | HSD17B1 (0.38) | JAK2NTRK1METFGFR1PRKACA | |
| SCHEMBL12628971 | 0.71 | PGR (0.38) | JAK2NTRK1METFGFR1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081688-A2 | 4-PHENYL-PYRANE-3,5-DIONES, 4-PHENYL-THIOPYRANE-3,5-DIONES AND CYCLOHEXANETRIONES AND THEIR USE AS INSECTICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | WO | disclosed |