Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223440 | 0.86 | ALDH1A1 (0.68) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL2546081 | 0.86 | ALDH1A1 (0.68) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL28539525 | 0.81 | ALDH1A1 (0.49) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL15630971 | 0.78 | KEAP1 (0.49) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL15519416 | 0.78 | MAPK1 (0.54) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL13161949 | 0.78 | HPGD (0.65) | HPGDALDH1A1MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL17194920 | 0.77 | HPGD (0.64) | HPGDALDH1A1MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL9078373 | 0.77 | TSHR (0.65) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL14802012 | 0.76 | MAPK1 (0.63) | HPGDALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL17748294 | 0.76 | ALOX5 (0.68) | HPGDALDH1A1MAPK1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2014-02-19 | — | — | EP | disclosed |
| WO-2012142513-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2012-10-18 | — | — | WO | disclosed |