Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 10/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.63 |
| ▸ | BRD4 | O60885 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | PTAFR | P25105 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615310 | 0.93 | GABRA1 (0.74) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL13285202 | 0.87 | BRD4 (0.77) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL11620188 | 0.84 | PTAFR (0.79) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL2615309 | 0.81 | GABRA5 (0.47) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL11400552 | 0.80 | PTAFR (0.48) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL9378858 | 0.78 | GABRA1 (0.71) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL14756888 | 0.78 | GABRA1 (0.71) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL11395364 | 0.78 | PTAFR (0.47) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL8250450 | 0.78 | GABRA1 (0.74) | GABRA5GABRA2GABRA1GABRB2GABRA3 | |
| SCHEMBL11839951 | 0.78 | GABRA1 (0.61) | GABRA5GABRA2GABRA1GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081036-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-15 | — | — | WO | disclosed |