Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782773 | 0.85 | MAPT (0.62) | MAPTTDP1HTTALDH1A1RAB9A | |
| SCHEMBL19705421 | 0.84 | MAPT (0.51) | MAPTTDP1HTTALDH1A1MAPK1 | |
| SCHEMBL12056258 | 0.83 | LMNA (0.48) | MAPTTDP1HTTALDH1A1RAB9A | |
| SCHEMBL851860 | 0.81 | MAPT (0.49) | MAPTTDP1HTTALDH1A1MAPK1 | |
| SCHEMBL1961466 | 0.80 | MAPT (0.55) | MAPTTDP1HTTALDH1A1RAB9A | |
| SCHEMBL2655336 | 0.79 | CES2 (0.45) | ALDH1A1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13607855 | 0.78 | MAPT (0.57) | MAPTTDP1HTTALDH1A1MRGPRX4 | |
| SCHEMBL17232506 | 0.78 | TUBB1 (0.36) | MAPTTDP1HTTRAB9ALMNA | |
| SCHEMBL1988162 | 0.77 | MAPT (0.51) | MAPTTDP1HTTALDH1A1RAB9A | |
| SCHEMBL1706655 | 0.77 | KEAP1 (0.47) | MAPTTDP1ALDH1A1CDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080537-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2010-07-15 | — | — | WO | disclosed |