Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PARG | Q86W56 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771758 | 0.84 | KMT2A (0.43) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL771759 | 0.84 | KMT2A (0.43) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL773215 | 0.76 | ALDH1A1 (0.57) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL1625381 | 0.75 | VCAM1 (0.70) | LMNAVCAM1ALDH1A1THRB | |
| SCHEMBL23092820 | 0.72 | ATM (0.49) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL29715252 | 0.68 | CA2 (0.65) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL18739981 | 0.68 | CA2 (0.65) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL3046201 | 0.68 | CA2 (0.65) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31647148 | 0.68 | ALDH1A1 (0.47) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL17749307 | 0.67 | WNK1 (0.66) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |