Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792205 | 0.87 | RECQL (0.40) | RECQLKMT2AGAARAB9ABRAF | |
| SCHEMBL13286249 | 0.84 | CHEK2 (0.39) | MAPK1HTR7HTR2B | |
| SCHEMBL13285969 | 0.78 | ROCK2 (0.36) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL13286176 | 0.76 | PLK1 (0.39) | SLC6A4 | |
| SCHEMBL13286175 | 0.74 | HSP90AA1 (0.48) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL13285984 | 0.74 | CA12 (0.39) | HTR7HTR2BALOX15 | |
| SCHEMBL13286258 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL13285986 | 0.74 | KDM4E (0.34) | LMNARAB9AMAPK1MAPTHSD17B10 | |
| SCHEMBL13286177 | 0.73 | HPGD (0.44) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13286262 | 0.73 | PDK2 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |