Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898018 | 1.00 | MAPT (0.33) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL1111229 | 0.85 | DRD1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL29528319 | 0.85 | DRD1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL1111225 | 0.85 | DRD1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL30220116 | 0.85 | DRD1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL15478440 | 0.85 | DRD1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498419 | 0.85 | SMN1; SMN2 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL12017252 | 0.84 | RAB9A (0.38) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498437 | 0.83 | MAPT (0.36) | MAPTNPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL14498430 | 0.81 | NPC1 (0.32) | MAPTNPC1RAB9ASMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061350-A1 | HYDROGENATION OF ESTER, KETONE OR ALDEHYDE GROUPS WITH RUTHENIUM COMPLEXES HAVING A DI-AMINE AND A PHOSPHOROUS-NITROGEN BIDENTATE LIGAND | FIRMENICH SA (CH) | 2010-06-03 | — | — | WO | disclosed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |