Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13288309 | 0.84 | MAPT (0.33) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 | |
| SCHEMBL17898018 | 0.84 | MAPT (0.33) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 | |
| SCHEMBL31048519 | 0.84 | MAPT (0.38) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 | |
| SCHEMBL28688006 | 0.83 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTCNR2 | |
| SCHEMBL28688009 | 0.83 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTCNR2 | |
| SCHEMBL28662764 | 0.83 | MAPT (0.38) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 | |
| SCHEMBL27848741 | 0.83 | MAPT (0.38) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 | |
| SCHEMBL14498459 | 0.83 | MAPT (0.38) | RAB9ANPC1SMN1; SMN2MAPTCNR2 | |
| SCHEMBL28703889 | 0.83 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTCNR2 | |
| SCHEMBL14648500 | 0.83 | ALOX15 (0.40) | RAB9ANPC1SMN1; SMN2MAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280623-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-09-29 | — | — | US | disclosed |
| US-9315525-B2 | Synthetic route for the preparation of α-amino boronic acid derivatives via substituted alk-1-ynes | LEK PHARMACEUTICALS D.D. (SI) | 2016-04-19 | — | — | US | disclosed |
| US-8785674-B2 | Process for hydrogenation of halogenoalkenes without dehalogenation | LEK PHARMACEUTICALS D.D. (SL) | 2014-07-22 | — | — | US | disclosed |
| US-20120231993-A1 | NEW SYNTHETIC ROUTE FOR THE PREPARATION OF ALPHA-AMINO BORONIC ACID DERIVATIVES via SUBSTITUTED ALK-1-YNES | LEK PHARMACEUTICALS D.D. (SI) | 2012-09-13 | — | — | US | disclosed |
| US-20120220794-A1 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | LEK PHARMACEUTICALS D.D. (SI) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220794-A1 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION | HDHD5, DEK, HCK | RAB9A 3050/4885NPC1 3437/4885SMN1; SMN2 4852/4885 |
| US-20160280623-A1 | ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST | IDH3B, IDH3A, CYP51A1 | RAB9A 2964/4885NPC1 2640/4885SMN1; SMN2 3117/4885 |
| US-20120231993-A1 | NEW SYNTHETIC ROUTE FOR THE PREPARATION OF ALPHA-AMINO BORONIC ACID DERIVATIVES via SUBSTITUTED ALK-1-YNES | ALK, ABL2, ALKBH3 | RAB9A 1785/4885NPC1 2759/4885SMN1; SMN2 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.