Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542762 | 0.89 | APP (0.35) | KDM4EAPPCYP1A2DRD3POLB | |
| SCHEMBL23701708 | 0.85 | APP (0.39) | KDM4EAPPCYP1A2PARP1 | |
| SCHEMBL13043492 | 0.85 | PTGES (0.36) | KDM4EPOLBLMNAMAPTGAA | |
| SCHEMBL13295296 | 0.85 | MAPT (0.36) | APPCYP1A2POLBLMNAMAPT | |
| SCHEMBL21678271 | 0.84 | APP (0.38) | APPCYP1A2 | |
| SCHEMBL14542763 | 0.82 | POLB (0.33) | KDM4EAPPCYP1A2DRD3POLB | |
| SCHEMBL10061229 | 0.79 | ALDH1A1 (0.36) | APPCYP1A2POLBLMNAMAPT | |
| SCHEMBL14542899 | 0.77 | POLB (0.35) | KDM4EPOLBLMNAMAPTMEN1 | |
| SCHEMBL14542900 | 0.77 | MAPT (0.36) | APPCYP1A2POLBLMNAMAPT | |
| SCHEMBL23675021 | 0.76 | APP (0.38) | KDM4EAPPCYP1A2PARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731760-B2 | Oxazine disulfide dyes | CIBA CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-20090229059-A1 | Oxazine Disulfide Dyes | CIBA CORP. | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090229059-A1 | Oxazine Disulfide Dyes | AOX1, CBR3, PRDX1 | KDM4E 4874/4885APP 2407/4885CYP1A2 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.