SCHEMBL13299554

SCHEMBL13299554

Cc1nc(-c2ccccc2)c(C)c(C)c1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
POLB P06746 2/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 1/20 0.57
KMT2A Q03164 1/20 0.57
XDH P47989 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
PDE10A Q9Y233 2/20 0.44
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.42
DHODH Q02127 1/20 0.42
MAPK14 Q16539 2/20 0.42
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945797 0.80 KDM4E (0.54) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL12388028 0.80 TDP1 (0.58) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL12377799 0.78 L3MBTL1 (0.54) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL26242505 0.77 MAOB (0.44) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL21388973 0.77 MAPT (0.47) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL21388967 0.77 MAPT (0.47) KDM4EALDH1A1POLBMAPTMEN1
Ammonia Solution, Strong SCHEMBL29007298 0.77 ALDH1A1 (0.52) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL23009767 0.76 L3MBTL1 (0.56) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL13114121 0.76 ALDH1A1 (0.55) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL13515891 0.76 KDM4E (0.50) KDM4EALDH1A1POLBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367223-B2 Heteroleptic phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 KDM4E 2674/4885ALDH1A1 695/4885POLB 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.