SCHEMBL12377799

SCHEMBL12377799

Cc1nc(-c2ccccc2)nc(-c2ccccc2)c1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 2/20 0.53
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 5/20 0.48
POLB P06746 4/20 0.48
RAB9A P51151 3/20 0.48
MEN1 O00255 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 1/20 0.48
PDE4B Q07343 1/20 0.46
PDE4D Q08499 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
DPP4 P27487 2/20 0.46
GLA P06280 1/20 0.46
ADK P55263 2/20 0.46
NPC1 O15118 1/20 0.46
HTT P42858 1/20 0.46
ADORA3 P0DMS8 4/20 0.44
ADORA2A P29274 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10375499 0.91 SMN1; SMN2 (0.57) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL10517881 0.89 DPP4 (0.54) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL10205915 0.89 L3MBTL1 (0.60) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL21895047 0.87 LMNA (0.46) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL10083704 0.87 L3MBTL1 (0.62) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL13114121 0.82 ALDH1A1 (0.55) L3MBTL1ALDH1A1KMT2APOLBRAB9A
SCHEMBL10205901 0.82 ADK (0.53) L3MBTL1LMNAALDH1A1KMT2ARAB9A
SCHEMBL21399367 0.80 LMNA (0.59) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL9818349 0.80 ALDH1A1 (0.51) L3MBTL1LMNAALDH1A1KMT2APOLB
SCHEMBL24715266 0.79 ALDH1A1 (0.50) L3MBTL1LMNAALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243101-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
EP-4242205-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
US-11758809-B2 Compound, display panel, and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-09-12 US disclosed
WO-2022191488-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-09-15 WO disclosed
WO-2022191681-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-09-15 WO disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device LAGE3, ICMT, PPOX L3MBTL1 1565/4885LMNA 1470/4885ALDH1A1 282/4885
US-11758809-B2 Compound, display panel, and display apparatus C1S, C3AR1, DRD3 L3MBTL1 3173/4885LMNA 3862/4885ALDH1A1 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.