SCHEMBL13301075

SCHEMBL13301075

CCO[Si](C)(C)CCCSC1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
LMNA P02545 4/20 0.39
MAPT P10636 3/20 0.39
HTT P42858 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
MDM2 Q00987 1/20 0.33
SLC2A1 P11166 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28058205 0.85 ALDH1A1 (0.40) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL770511 0.75
SCHEMBL5703252 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL10775300 0.72 CYP1A2 (0.44) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL10774762 0.72 CYP1A2 (0.44) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL329132 0.72 CYP1A2 (0.44) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL13266798 0.72 CYP1A2 (0.44) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL15977058 0.72
SCHEMBL108269 0.72
SCHEMBL10774246 0.70 CYP1A2 (0.43) ALDH1A1LMNAMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100145089-A1 PREPARATION OF (POLY)SULFIDE ALKOXYSILANES AND NOVEL INTERMEDIATES THEREFOR RHODIA OPERATIONS (FR) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145089-A1 PREPARATION OF (POLY)SULFIDE ALKOXYSILANES AND NOVEL INTERMEDIATES THEREFOR TST, CTH, CBS ALDH1A1 1885/4885LMNA 4645/4885MAPT 4046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.