Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102738 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16526158 | 0.79 | — | — | |
| SCHEMBL14421414 | 0.77 | — | — | |
| SCHEMBL4430293 | 0.77 | — | — | |
| SCHEMBL4430295 | 0.77 | — | — | |
| SCHEMBL183909 | 0.77 | — | — | |
| SCHEMBL183908 | 0.77 | — | — | |
| SCHEMBL12715408 | 0.73 | — | — | |
| SCHEMBL2780464 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL2780466 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | claimed |
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2024-02-15 | — | — | US | claimed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | claimed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | claimed |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | disclosed |
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2024-02-15 | — | — | US | disclosed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | disclosed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | disclosed |
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | CYP2J2, CLK2, CLK1 | SMN1; SMN2 4089/4885RAB9A 3345/4885ALDH1A1 316/4885 |
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CYP51A1, ERG28, CYP3A7 | SMN1; SMN2 3795/4885RAB9A 2101/4885ALDH1A1 1486/4885 |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | CYP2J2, CLK2, CLK1 | SMN1; SMN2 4089/4885RAB9A 3345/4885ALDH1A1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.