Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | KIF20A | O95235 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13694239 | 0.82 | MCL1 (0.47) | MCL1KDM4EMEN1MAPTTSHR | |
| SCHEMBL13292073 | 0.79 | PTGES (0.34) | AHRPTGESJAK2TBXAS1CYP2A6 | |
| SCHEMBL14153895 | 0.79 | KIF11 (0.38) | MCL1CYP2A6GABRA1GABRG2GABRB3 | |
| SCHEMBL14153894 | 0.76 | KIF11 (0.44) | MCL1TSHRSMN1; SMN2 | |
| SCHEMBL10296321 | 0.76 | MCL1 (0.48) | MCL1KDM4EMEN1MAPTTSHR | |
| SCHEMBL19977161 | 0.73 | AHR (0.54) | AHRPTGESJAK2TBXAS1CYP2A6 | |
| SCHEMBL21764494 | 0.73 | AHR (0.54) | AHRPTGESJAK2TBXAS1CYP2A6 | |
| SCHEMBL9174497 | 0.73 | AHR (0.54) | AHRPTGESJAK2TBXAS1CYP2A6 | |
| SCHEMBL15233537 | 0.70 | KIF11 (0.45) | MCL1MEN1MAPTALOX15KMT2A | |
| SCHEMBL23346236 | 0.69 | ALOX5 (0.39) | MCL1JAK2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745083-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090297218-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-12-03 | — | — | US | disclosed |
| US-7592113-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080233499-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-09-25 | — | — | US | disclosed |