Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292099 | 0.89 | CES2 (0.37) | MAPTXPO1CYP1A2CYP3A4CES2 | |
| SCHEMBL2090002 | 0.82 | KDM4E (0.42) | MAPTKDM4ECYP1A2CYP3A4MAPK1 | |
| SCHEMBL13292097 | 0.75 | CES1 (0.55) | MAPTCYP3A4MAPK1CES2 | |
| SCHEMBL12109882 | 0.74 | MAPT (0.43) | MAPTHSP90AA1 | |
| SCHEMBL3437808 | 0.72 | ALDH1A1 (0.44) | MAPTHSP90AA1KDM4ECYP1A2MAPK1 | |
| SCHEMBL31211721 | 0.72 | ALDH1A1 (0.44) | MAPTHSP90AA1KDM4ECYP1A2MAPK1 | |
| SCHEMBL13694202 | 0.69 | MAOA (0.52) | NOTUMMAPTHSP90AA1 | |
| SCHEMBL13319595 | 0.68 | ALDH1A1 (0.61) | MAPTKDM4ECYP3A4MAPK1CES2 | |
| SCHEMBL107119 | 0.66 | RAPGEF4 (0.56) | RAPGEF4NOTUMMAPTXPO1IDH1 | |
| SCHEMBL130017 | 0.66 | RAPGEF4 (0.50) | RAPGEF4NOTUMMAPTXPO1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745083-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090297218-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-12-03 | — | — | US | disclosed |
| US-7592113-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080233499-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-09-25 | — | — | US | disclosed |
| US-7396622-B2 | Having a charge generation layer containing a phenanthrene compound, a phenanthroline compound or an acenaphthene compound that has two oxo-, phenylimino- or dicyanovinylene groups that may be the same or different; charge-generating material is preferably hydroxygallium phthalocyanine. | CANON KABUSHIKI KAISHA (JP) | 2008-07-08 | — | — | US | disclosed |