Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RHOC | P08134 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302411 | 0.93 | ALDH1A1 (0.39) | HMGCRALDH1A1 | |
| SCHEMBL13302361 | 0.84 | HMGCR (0.42) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL13302360 | 0.80 | HMGCR (0.57) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9764095 | 0.80 | ALDH1A1 (0.43) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9658354 | 0.79 | ALDH1A1 (0.41) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL9764185 | 0.78 | KDM4E (0.48) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL12758829 | 0.77 | ALDH1A1 (0.44) | HMGCRABCB11SLCO1B1HDAC1HDAC2 | |
| SCHEMBL13302235 | 0.77 | HMGCR (0.34) | HMGCR | |
| SCHEMBL9764313 | 0.74 | PTGS2 (0.43) | HMGCRKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9764104 | 0.72 | ALDH1A1 (0.45) | CYP3A4KDM4EALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145046-A1 | Substituted 3-hydroxy-delta-lactones from epoxides | ENERGY, UNITED STATES DEPARTMENT OF | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145046-A1 | Substituted 3-hydroxy-delta-lactones from epoxides | EBP, CYP8B1, HSD3B2 | HMGCR 160/4885ABCB11 4565/4885SLCO1B1 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.