Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764095 | 0.95 | ALDH1A1 (0.43) | PTGS2ALDH1A1HMGCRL3MBTL1KDM4E | |
| SCHEMBL9319959 | 0.84 | ALDH1A1 (0.39) | PTGS2ALDH1A1HMGCRMAPK14GCGR | |
| SCHEMBL9756723 | 0.82 | PTGS2 (0.39) | PTGS2ALDH1A1HMGCRL3MBTL1KDM4E | |
| SCHEMBL9756726 | 0.82 | PTGS2 (0.39) | PTGS2ALDH1A1HMGCRL3MBTL1KDM4E | |
| SCHEMBL9024278 | 0.82 | PTGS2 (0.38) | PTGS2ALDH1A1HMGCRMAPK14 | |
| SCHEMBL9764106 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4ETDP1LMNA | |
| SCHEMBL9658354 | 0.80 | ALDH1A1 (0.41) | PTGS2ALDH1A1HMGCRRIPK3L3MBTL1 | |
| SCHEMBL9764185 | 0.79 | KDM4E (0.48) | ALDH1A1HMGCRRIPK3L3MBTL1KDM4E | |
| SCHEMBL12758829 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HMGCRL3MBTL1KDM4ETDP1 | |
| SCHEMBL9320007 | 0.76 | GCGR (0.43) | ALDH1A1HMGCRMAPK14GCGRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |