Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303488 | 0.80 | DPP4 (0.54) | DPP4CDK2 | |
| SCHEMBL3263477 | 0.78 | LCK (0.45) | DPP4 | |
| SCHEMBL3260799 | 0.76 | BTK (0.47) | DPP4 | |
| SCHEMBL3263368 | 0.76 | DPP4 (0.40) | DPP4 | |
| SCHEMBL19981572 | 0.70 | BTK (0.44) | — | |
| SCHEMBL19981933 | 0.70 | BTK (0.44) | — | |
| SCHEMBL13303603 | 0.69 | SYK (0.48) | — | |
| SCHEMBL13303496 | 0.68 | DPP4 (0.63) | DPP4CDK2 | |
| SCHEMBL21946915 | 0.67 | LCK (0.46) | — | |
| SCHEMBL13118839 | 0.65 | CDK2 (0.77) | DPP4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068806-A1 | AMIDE DERIVATIVES AS BTK INHIBITORS IN THE TREATMENT OF ALLERGIC, AUTOIMMUNE AND INFLAMMATORY DISORDERS AS WELL AS CANCER | CGI PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | disclosed |