Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953405 | 0.85 | CDK2 (0.40) | KDM4EALDH1A1MAPTRAB9APLAT | |
| SCHEMBL13304791 | 0.81 | GSK3B (0.39) | ALDH1A1MAPT | |
| SCHEMBL12952988 | 0.77 | PDE10A (0.50) | — | |
| SCHEMBL13146264 | 0.72 | CDK2 (0.37) | — | |
| SCHEMBL13304835 | 0.72 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL13304711 | 0.70 | HTR6 (0.35) | — | |
| SCHEMBL14597986 | 0.69 | PDE10A (0.33) | — | |
| SCHEMBL13305063 | 0.68 | PSD (0.40) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL13304689 | 0.67 | MAPT (0.35) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL13305010 | 0.66 | CCNT1 (0.41) | KDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |